Autonomous, radiation-free bronchoscopic navigation for deep lung access

LumenGuides

Introducing NaviScope™

A novel AI-assisted robotic bronchoscopic navigation platform enabling real-time, intraluminal 3D airway reconstruction without radiation or external imaging.

Radiation-free navigation

Real-time intraluminal 3D mapping

Single-use sterile system

Designed for the FDA 510(k) regulatory pathway

Product Overview

LumenGuides is developing NaviScope™, an AI-assisted robotic bronchoscopic navigation platform designed to address one of pulmonary medicine's most persistent challenges: accurate, radiation-free access to deep peripheral lung lesions.

Unlike existing navigation systems that rely on fluoroscopy, electromagnetic tracking, or intra-procedural CT, NaviScope™ uses fiber-optic shape sensing based on Fiber Bragg Gratings (FBG) combined with proprietary signal processing, real-time geometric reconstruction, and AI-driven navigation algorithms.

This approach enables continuous, real-time 3D reconstruction of the airway tree directly from within the lumen, without radiation, external imaging, or room-dependent infrastructure.

FDA PATHWAY

Designed for the 510(k) regulatory pathway

Key Technical Differentiators

Technology designed to advance bronchoscopic navigation and diagnostic reach.

True Real-Time Intraluminal 3D Airway Mapping

Continuous geometric reconstruction of the airway tree generated directly from within the lumen.

Continuous CT-to-Live Registration

Seamless alignment between pre-procedure CT imaging and live intraluminal sensing data.

AI-Assisted Autonomous Navigation

Intelligent navigation designed to reduce physician cognitive load while maintaining clinician oversight.

Single-Use Sterile Robotic System

Compatible with standard working channels and designed to reach lesions beyond conventional bronchoscopy.

Our Mission

We are a team of experienced entrepreneurs and medical innovators focused on improving outcomes in minimally invasive lung diagnostics.

Today, up to 35% of lung biopsies require invasive surgical procedures due to limitations in bronchoscopic access. NaviScope™ is designed to reduce that burden through radiation-free, AI-assisted navigation.

With a validated proof of concept, LumenGuides is advancing toward clinical translation in a large and underserved global market.

$62.5B

Global Market

500K+

Annual U.S. Procedures

35%

Cases with potential for improvement

Why Choose LumenGuides

Precision Navigation

Designed for accurate, real-time navigation within complex pulmonary anatomy.

AI Integration

Combining optical sensing with intelligent algorithms to support safer procedures.

Patient-Centric Design

Focused on reducing invasiveness, radiation exposure, and overall procedural burden.

Watch Now

LumenGuides Video

Watch our latest presentation on how NaviScope™ is transforming bronchoscopy procedures

Learn how LumenGuides is pioneering the future of minimally invasive lung diagnostics

Advanced Technology

NaviScope™

Autonomous, radiation-free bronchoscopic navigation powered by intraluminal optical sensing and AI

Current State

The Problem

Despite significant advances in pulmonology, current bronchoscopic navigation technologies remain constrained by limited accuracy, complex workflows, and reliance on radiation-based imaging—resulting in suboptimal diagnostic yield and increased patient risk.

8mm+

Limited Detection Capability

Most existing systems struggle to reliably localize and access pulmonary nodules smaller than 8mm, increasing the risk of false negatives and delayed diagnosis.

☢️

Radiation Dependence

Fluoroscopy and intra-procedural CT expose both patients and clinicians to cumulative ionizing radiation during navigation.

40%

Limited Peripheral Reach

Up to 40% of lung biopsies still require invasive surgical intervention due to insufficient access to deep peripheral airways.

$20K+

High Procedural Costs

Radiation-based imaging, operating room dependency, and surgical alternatives significantly increase procedural cost and patient burden.

Innovation

Our Solution

NaviScope™ is a novel AI-assisted robotic bronchoscopic navigation platform designed to enable precise, radiation-free access to deep peripheral lung lesions.

Unlike conventional navigation systems that depend on electromagnetic tracking or external imaging, NaviScope™ is based on fiber-optic shape sensing using Fiber Bragg Gratings (FBG) combined with proprietary signal processing, real-time geometric reconstruction, and AI-driven navigation algorithms.

🔬

Intraluminal Optical Fiber Integration

FBG shape-sensing fibers embedded directly within the bronchoscope provide continuous geometric awareness from inside the airway.

📍

Real-Time Shape & Position Reconstruction

Continuous, high-resolution reconstruction of bronchoscope geometry within complex pulmonary airways.

🗺️

Live 3D Airway Mapping with CT Registration

Real-time registration between pre-procedure CT data and intraluminal sensing enables intuitive and accurate navigation.

🛡️

Radiation-Free, AI-Assisted Navigation

Navigation without fluoroscopy or intra-procedural CT, while reducing physician cognitive load through intelligent guidance.

Advantages

Product Benefits

Delivering meaningful improvements in diagnostic reach, safety, and procedural efficiency.

1mm

High Precision Targeting

Designed to detect and navigate toward lesions as small as 1mm.

Radiation-Free Navigation

No ionizing radiation required during the navigation phase.

95%+

Expanded Lung Accessibility

Designed to reach deep peripheral lesions beyond the limits of conventional bronchoscopy.

-60%

Cost Reduction Potential

Reduced reliance on invasive procedures and imaging-heavy infrastructure.

Impact

Why It Matters

A meaningful shift in lung diagnostics with broad impact across patient care and healthcare systems.

🎯

Earlier detection enables better outcomes and lower overall cost of care

🔍

Supports diagnosis at earlier stages of lung cancer

💊

Reduces dependence on chemotherapy and invasive surgical intervention

❤️

Improves patient safety, recovery time, and quality of life

Our Team

Team

Meet the visionary leaders driving innovation in medical technology and transforming patient care

Founder & CEO

Limor Prigan

ChE, MBA

Global Biz Dev experience at FUJIFILM USA, Ames Aerospace USA, Avertto Medical IL, Kornit Digital

Founder & CTO

Yaniv Kirma

BSc. EE, Physics

Successful exits at Fibernova (acquired by Broncus Medical)

Co-founder & CMO

Prof. Doron Kopelman

Former Head of Surgery at Technion, President of Israeli Surgical Association ISA

CFO

Smadar Haviv

CPA, MBA

> 20 years of experience across public, private, and nonprofit sectors.

CRO

Dr. Ornit Yanai-Kohelet

CEO and managing director of Q-Trials

CQO

Kety Bardugo

Quality and regulatory affairs expert

COO

Robby Dascalo

Operations and strategic management leader

USA Business Development

Dan Vigdor

Strategic business development and market expansion specialist

Advisory Board

Distinguished medical experts guiding our clinical development and innovation

Head of Interventional Pulmonary

Dr. Shai Amor

Expert in interventional pulmonary procedures

Head of Pulmonary

Dr. Amir Bar-Shai

Leading pulmonary medicine specialist

IL Head of Radiology & Vascular

Prof. Eli Atar

Expert in radiology and vascular interventions

IL Head of Pulmonary

Prof. Mordechai Kramer

Performed ~1000 lung transplants

USA Head of Robotic Pulmonary

Prof. Sanket Thakore

Leading expert in robotic pulmonary procedures

Get In Touch

Contact LumenGuides

Ready to revolutionize bronchoscopy? Get in touch with our team to learn more about our innovative NaviScope™ system.